14th Day and Prize for Clinical Research Thursday, May 6, 2021 Winners of the Clinical Research Prize
This year, two winners were exceptionally rewarded ex quo:
Dr David Legouis (link is external) for the study "Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality" published in the journal Nature (link is external). This study shows that renal gluconeogenesis is strongly impaired in acute renal failure and leads to the appearance of an abnormal systemic metabolic profile, combining hyperlactatemia and hypoglycemia. This profile is associated with increased mortality in intensive care.
Elodie Von Dach (link is external), doctor of public health, for the PIRATE study published in the Journal of the American Medical Association (link is external) (or "Effect of C-Reactive Protein-Guided Antibiotic Treatment Duration, 7- Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial "). This multicenter randomized-controlled clinical trial was conducted with 504 patients in Geneva, Lausanne and St. Gallen, with funding from the Swiss National Science Foundation. In the case of simple Gram-negative bacteremia, this study demonstrates the non-inferiority of a duration of antibiotic treatment guided by CRP (C-reactive protein) or of 7 days compared to a treatment of 14 days.
Medicine and gender award
The new Medicine and Gender Prize aims to distinguish research projects evaluating the influence of sex and / or gender on health. It was awarded to Dr. Jasmine Abdulcadir (link is external) for her 3D model kit project presenting female and male sexual anatomy ("In Vivo ImagingeBased 3-Dimensional Pelvic Prototype Models to Improve Education Regarding Sexual Anatomy and Physiology" ). Unveiled in a study published in the Journal of Sexual Medicine (link is external), these precise and realistic anatomical structures show the male and female anatomy as a whole. They may be offered in the teaching of sexual anatomy to health professionals, in schools and clinics, and to the general public.
The public vote went to Dr Julien Haemmerli (link is external) for the poster "Evaluation of the precision of operative augmented reality compared to standard neuronavigation using a 3D-printed skull (link is external)". This study published in the Journal of Neurosurgery (link is external) demonstrates the superiority of the use of augmented reality in cranial surgery, in terms of precision, compared to conventional neuronavigation.
Richness and diversity of research at HUG
The aim of the day of clinical research is to promote and encourage research, create synergies and encourage vocations. The success of this new edition, despite the constraints related to the health situation, demonstrates the vitality of clinical research if there was still a need for it.
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Conference Pr. Matthias Briel, Deputy Director of the Basel Institute for Clinical Epidemiology and Biostatistics (CEB), Department of Clinical Research, University Hospital Basel "COVID-19 and clinical research - time to get more efficient (link is external)"